DeGAUSS (Decentralized Geomarker Assessment for Multi-Site Studies) is a decentralized method for geocoding and deriving community and individual level environmental characteristics while maintaining the privacy of protected health information. It is a standalone and versatile software application based on containerization. This means that geomarker assessment is reproducible, standardized, and can be computed on at scale. Importantly, DeGAUSS is executable on a local machine – it does not require extensive computational resources and PHI is never exposed to a third party or the internet, making it ideal for geomarker assessment in a multi-site study.


Get started using DeGAUSS with the Using DeGAUSS guide. If you have any questions or problems, please first see our troubleshooting guide and then open an issue within the corresponding GitHub repository.

If you have used DeGAUSS, would you mind giving us some quick feedback?


If you use this software in a scientific publication, please consider citing one of our publications:

Supported By

Trusted By